Myasthenia Gravis

Myasthenia gravis (MG) is a chronic autoimmune neuromuscular disorder that weakens voluntary muscles due to impaired communication between nerves and muscles. It occurs when antibodies block or destroy acetylcholine receptors, preventing muscle contraction. Symptoms include muscle weakness, drooping eyelids (ptosis), difficulty swallowing, slurred speech, and fatigue that worsens with activity. There is no cure, but treatments such as acetylcholinesterase inhibitors (e.g., pyridostigmine), corticosteroids, immunosuppressants, and plasmapheresis help manage symptoms.